課程資訊
課程名稱
專題討論
Seminar 
開課學期
108-2 
授課對象
生化科技研究所  
授課教師
廖憶純 
課號
BST7000 
課程識別碼
B22 M0020 
班次
02 
學分
1.0 
全/半年
半年 
必/選修
必修 
上課時間
星期四8,9(15:30~17:20) 
上課地點
 
備註
必修4學期。上課地點:共同102。與黃楓婷、鄭梅君合授
限碩士班以上
總人數上限:42人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1082BST7000_02 
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課程概述

專題討論二 

課程目標
待補 
課程要求
待補 
預期每週課後學習時數
 
Office Hours
 
指定閱讀
待補 
參考書目
待補 
評量方式
(僅供參考)
   
課程進度
週次
日期
單元主題
第1週
3/05  Master Day (系五教室) 
第2週
3/12  李怡萱 Puerarin inhibits inflammation and oxidative stress in dextran sulfate sodium-induced colitis mice model. Biomed Pharmacother. 124:109847 (2020)
黃政睿 Monoubiquitination of p120-catenin is essential for TGFβ-induced epithelial-mesenchymal transition and tumor metastasis. Sci. Adv. 6:eaay9819 (2020) 
第3週
3/19  簡宏廷 miR-21 may Act as a Potential Mediator Between Inflammation and Abnormal Bone Formation in Ankylosing Spondylitis Based on TNF-alpha Concentration-Dependent Manner Through the JAK2/STAT3 Pathway. Dose Response 18:1559325819901239 (2020)
邱筱茹 Beta-Catenin/Tcf7l2-Dependent Transcriptional Regulation of GLUT1 Gene Expression by Zic Family Proteins in Colon Cancer. Sci. Adv. 5:eaax0698 (2019) 
第4週
3/26  賴冠錞 PROTAC induced-BET protein degradation exhibits potent anti-osteosarcoma activity by triggering apoptosis. Cell Death Dis. 10:815 (2019)
鄧家蓉 A Novel Nanobody Targeting Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Receptor-Binding Domain Has Potent Cross-Neutralizing Activity and Protective Efficacy against MERS-CoV. J. Virol. 92:18 e00837-18 (2018) 
第5週
4/02  兒童節補假 
第6週
4/09  高先穎 Endometrial Axin2+ Cells Drive Epithelial Homeostasis, Regeneration, and Cancer following Oncogenic Transformation. Cell Stem Cell 26:64-80 (2020)
陳姿吟 The G Protein -Subunit, AGB1, Interacts with FERONIA in RALF1-Regulated Stomatal Movement. Plant Physiol. 176:2426-2440 (2018)
蘇俊熙 PRH1 mediates ARF7-LBD dependent auxin signaling to regulate lateral root development in Arabidopsis thaliana. PLoS Genet. 16:e1008044 (2020) 
第7週
4/16  曾翊翔 Long noncoding RNA AC003092.1 promotes temozolomide chemosensitivity through miR-195/TFPI-2 signaling modulation in glioblastoma. Cell Death Dis 9:1139 (2018)
林欣誼 PERK-mediated expression of peptidylglycine α-amidating monooxygenase supports angiogenesis in glioblastoma. Oncogenesis. 9:18 (2020) 
第8週
4/23  吳冠怡 Disordered region of cereblon is required for efficient degradation by proteolysis-targeting chimera. Sci. Rep. 9, Article number: 19654 (2019)
王子維 Circadian and sleep/wake-dependent variations in tau phosphorylation are driven by temperature. Sleep. pii: zsz266 (2019) 
第9週
4/30  周維謙 Bacterial Outer Membrane Vesicles (OMVs)-based Dual Vaccine for Influenza A H1N1 Virus and MERS-CoV. Vaccines 7:46 (2019)
廖紘陞 Nitrate modulates stem cell dynamics in Arabidopsis shoot meristems through cytokinins. Proc Natl Acad Sci U S A. 115: 1382-1387 (2018) 
第10週
5/07  陳琳瑄 PDIA6 regulates insulin secretion by selectively inhibiting the RIDD activity of IRE1. FASEB J. 30: 653-665 (2016)
林頁彤 Using Tetracysteine-Tagged TDP-43 with a Biarsenical Dye To Monitor Real-Time Trafficking in a Cell Model of Amyotrophic Lateral Sclerosis. Biochemistry 58:4086-95 (2019)
尤恩 Insulin–Insulin-like Growth Factors Hybrids as Molecular Probes of Hormone:Receptor Binding Specificity. Biochemistry 55:2903-2913 (2016) 
第11週
5/14  林家伃 ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway. Nat. Cell Biol. 21: 579–591 (2019)
莊佳寶 TRIM25 promotes the cell survival and growth of hepatocellular carcinoma through targeting Keap1-Nrf2 pathway. Nat Commun. 11:348 (2020) 
第12週
5/21  羅宇茜 IRE1B degrades RNAs encoding proteins that interfere with the induction of autophagy by ER stress in Arabidopsis thaliana. Autophagy. 14:1562-1573 (2018)
吳孟庭 An order-to-disorder structural switch activates the FoxM1 transcription factor. eLife 8:e46131. (2019) 
第13週
5/28  呂湘庭 KDM3A Senses Oxygen Availability to Regulate PGC1α-Mediated Mitochondrial Biogenesis. Mol. Cell 76: 885-895 (2019)
賴宣妤 TOR Signaling Promotes Accumulation of BZR1 to Balance Growth with Carbon Availability in Arabidopsis.
Curr. Biol. 26:1854-1860 (2016) 
第14週
6/04  許嘉珈 Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells. Science 360 (6391): eaan5931 (2018)
張法理 ATP binding cassette transporters ABCG1 and ABCG16 affect reproductive development via auxin signalling in Arabidopsis. Plant J. (2020)
趙伯宣 Intrinsically disordered proteins drive membrane curvature. Nat Commun 6: 7875 (2015) 
第15週
6/11  鄭洛凡 MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancer. Br J Cancer (2020). Published date: 16 January 2020
陳沚郁 Targeting lipid metabolism to overcome EMT- associated drug resistance via integrin β3FAK pathway and tumor-associated macrophage polarization using legumain-activatable delivery. Theranostics. 9: 265-278 (2019) 
第16週
6/18  林偉康 Overexpression of microRNA-155 enhances the efficacy of dendritic cell vaccine against breast cancer. Oncoimmunology 9:e1724761 (2020)
陳姿廷 Identification of a Chlorophyll Dephytylase Involved in Chlorophyll Turnover in Arabidopsis. Plant Cell. 28: 2974-2990 (2016) 
第17週
6/25  端午節放假